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Podcast · Technology
Latent Space: The AI Engineer Podcast
Latent.Space
50 episodes available · plays inline · no app required
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The Inference Engineering Masterclass — Philip Kiely & Ali Taha, Baseten
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Codex from 0 to 10M Users: Building ChatGPT Work — Akshay Nathan, OpenAI
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Inside the Model Factory — Eiso Kant, Poolside AI
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🔬Causal Models Need Causal Data - Xaira’s X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist)
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🔬 The Lab of the Future Should Feel Like a Data Center — Andy Beam & Rafa Gómez-Bombarelli, Lila Sciences
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Why AI Infrastructure must evolve for Agent Experience — Akshat Bubna, Modal CTO
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🔬 The Coolest Diffusion Research Isn't in LLMs — Evan Feinberg & Sergey Edunov, Genesis Molecular AI
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Why the Frontier Ecosystem must be Open — Matei Zaharia and Reynold Xin, Databricks
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Red-Teaming after Mythos — Zico Kolter & Matt Fredrikson, Gray Swan
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The Professor of Outputmaxxing — Anjney Midha, AMP
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🔬 The Self-Driving Lab — Joseph Krause, Radical AI
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Reality: The Final Eval — Lukas Petersson and Axel Backlund of Andon Labs
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🔬Scaling Past Informal AI - Carina Hong, Axiom Math
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⚡️Satya Nadella: No Priors x Latent Space Crossover Special at Microsoft Build
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GitHub's plan for Agents — Kyle Daigle, GitHub
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Why Video Agent models are next — Ethan He, xAI Grok Imagine
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The Age of Async Agents — Cognition's Walden Yan & OpenInspect's Cole Murray
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🔬ESM: The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub
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Giving Agents Computers — Ivan Burazin, Daytona
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Railway: The Agent-Native Cloud — Jake Cooper
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The Autonomous Drone Tech Stack & Economics of Drones — Yaroslav Azhnyuk, The Fourth Law & Guest Host Noah Smith, Noahpinion
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AI-Native Healthcare: 100M Doctor Visits, 10–20 Hours Saved, Prior Auth in Minutes — Janie Lee & Chai Asawa, Abridge
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🔬Doing Vibe Physics — Alex Lupsasca, OpenAI
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Physical AI that Moves the World — Qasar Younis & Peter Ludwig, Applied Intuition
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AIE Europe Debrief + Agent Labs Thesis: Unsupervised Learning x Latent Space Crossover Special (2026)
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Shopify’s AI Phase Transition: 2026 Usage Explosion, Unlimited Opus-4.6 Token Budget, Tangle, Tangent, SimGym — with Mikhail Parakhin, Shopify CTO
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🔬 Training Transformers to solve 95% failure rate of Cancer Trials — Ron Alfa & Daniel Bear, Noetik
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Notion’s Token Town: 5 Rebuilds, 100+ Tools, MCP vs CLIs and the Software Factory Future — Simon Last & Sarah Sachs of Notion
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Extreme Harness Engineering for Token Billionaires: 1M LOC, 1B toks/day, 0% human code, 0% human review — Ryan Lopopolo, OpenAI Frontier & Symphony
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Marc Andreessen introspects on The Death of the Browser, Pi + OpenClaw, and Why "This Time Is Different"
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Moonlake: Causal World Models should be Multimodal, Interactive, and Efficient — with Chris Manning and Fan-yun Sun
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Mistral: Voxtral TTS, Forge, Leanstral, & what's next for Mistral 4 — w/ Pavan Kumar Reddy & Guillaume Lample
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🔬Why There Is No "AlphaFold for Materials" — AI for Materials Discovery with Heather Kulik
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Dreamer: the Personal Agent OS — David Singleton
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Why Anthropic Thinks AI Should Have Its Own Computer — Felix Rieseberg of Claude Cowork & Claude Code Desktop
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Retrieval After RAG: Hybrid Search, Agents, and Database Design — Simon Hørup Eskildsen of Turbopuffer
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NVIDIA's AI Engineers: Agent Inference at Planetary Scale and "Speed of Light" — Nader Khalil (Brev), Kyle Kranen (Dynamo)
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Cursor's Third Era: Cloud Agents
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Every Agent Needs a Box — Aaron Levie, Box
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METR’s Joel Becker on exponential Time Horizon Evals, Threat Models, and the Limits of AI Productivity
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[LIVE] Anthropic Distillation & How Models Cheat (SWE-Bench Dead) | Nathan Lambert & Sebastian Raschka
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🔬Searching the Space of All Possible Materials — Prof. Max Welling, CuspAI
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Claude Code for Finance + The Global Memory Shortage: Doug O'Laughlin, SemiAnalysis
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⚡️The End of SWE-Bench Verified — Mia Glaese & Olivia Watkins, OpenAI Frontier Evals & Human Data
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Bitter Lessons in Venture vs Growth: Anthropic vs OpenAI, Noam Shazeer, World Labs, Thinking Machines, Cursor, ASIC Economics — Martin Casado & Sarah Wang of a16z
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Owning the AI Pareto Frontier — Jeff Dean
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🔬Beyond AlphaFold: How Boltz is Open-Sourcing the Future of Drug Discovery
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The First Mechanistic Interpretability Frontier Lab — Myra Deng & Mark Bissell of Goodfire AI
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🔬 Automating Science: World Models, Scientific Taste, Agent Loops — Andrew White
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Captaining IMO Gold, Deep Think, On-Policy RL, Feeling the AGI in Singapore — Yi Tay
